ProteinTech/CDK3多克隆抗体/150ul/55103-1-AP
商品编号：
55103-1-AP
品牌：
ptglab
市场价：
¥1980.00
美元价：
1188.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Tested Applications
| Positive WB detected in | mouse brain tissue, MCF-7 cells,Jurkat cells,rat brain tissue |
| Positive IHC detected in | human breast cancer tissueNote: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunohistochemistry (IHC) | IHC : 1:100-1:400 |
| Sample-dependent, check data in validation data gallery | |
Published Applications
| WB | See 1 publications below |
Product Information
55103-1-AP targets CDK3 inWB, IHC, ELISA applications and shows reactivity with human,mouse samples.
| Tested Reactivity | human,mouse |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide |
| Full Name | cyclin-dependent kinase 3 |
| Calculated molecular weight | 35 kDa |
| Observed molecular weight | 40-45 kDa |
| GenBank accession number | NM_001258 |
| Gene symbol | CDK3 |
| Gene ID (NCBI) | 1018 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | 0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for-20oC storage. |
Background Information
CDK3 belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It is probably involved in the control of the cell cycle. CDK3 interacts with a yet unknown type of cyclin. It can phosphorylate histone H1. Endogenous Cyclin C/Cdk3 complexes are critical to promote exit from quiescence in an Rb-dependent manner. Cyclin C/Cdk3 complexes is a key regulators of cell cycle reentry in human cells. (PMID: 15130482 )The antibody is specific to CDK3.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for CDK3 antibody 55103-1-AP | Download protocol |
| IHC protocol for CDK3 antibody 55103-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
品牌介绍
Proteintech Group 由一群当时积极从事 NIH 资助研究的科学家于 2001 年创立。最初的创始人之一和现任首席执行官 Jason Li 博士在公司成立期间是伊利诺伊大学芝加哥分校的免疫学副教授。他谈到 Proteintech 成立背后的原因：“我们抱负的核心是一家由科学家组成的公司；一家为研究人员提供优势的抗体供应商，而不是投资者。”原创产品 – 原创产品Proteintech Group 的部分早期愿景是按照可能的最高标准生产自己的所有产品，并且从不从任何其他供应商处采购单一抗体。这将为研究人员提供许多优势，包括避免由不同公司以不同品牌出售相同抗体的方法——这是行业内出现的一种不受监管的做法1。Proteintech 以 100% 的原创产品为客户提供真诚和正直的品质，您将在本手册中不断发现这些品质。您只能直接从 Proteintech 或通过其批准的经销商之一购买 Proteintech 抗体 - 当您收到抗体并看到小瓶上的 Proteintech 标志时，请知道您拥有真正独一无二的东西。
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